Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes.

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第一作者： Ramasubramanian,Sundaramoorthy

第一单位： Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, United Kingdom.

作者： Ramasubramanian,Sundaramoorthy ^[1] ; Amanda L,Hughes ^[1] ; Vijender,Singh ^[1] ; Nicola,Wiechens ^[1] ; Daniel P,Ryan ^[1] ; Hassane,El-Mkami ^[2] ; Maxim,Petoukhov ^[3] ; Dmitri I,Svergun ^[3] ; Barbara,Treutlein ^[4] ; Salina,Quack ^[4] ; Monika,Fischer ^[4] ; Jens,Michaelis ^[4] ; Bettina,Böttcher ^[5] ; David G,Norman ^[6] ; Tom,Owen-Hughes ^[1]

作者单位： Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, United Kingdom. ^[1] School of Physics and Astronomy, University of St Andrews, St Andrews, United Kingdom. ^[2] Hamburg Outstation, European Molecular Biology Laboratory, Hamburg, Germany. ^[3] Institute for Biophysics, Faculty of Natural Sciences, Ulm University, Ulm, Germany. ^[4] Lehrstuhl für Biochemie, Rudolf-Virchow Zentrum, Universitat Würzburg, Würzburg, Germany. ^[5] Nucleic Acids Structure Research Group, University of Dundee, Dundee, United Kingdom. ^[6]

关键词 ATPase Chd1 S. cerevisiae biophysics chromatin remodeling chromosomes genes nucleosome structural biology