Stereoselective synthesis of novel adamantane derivatives with high potency against rimantadine-resistant influenza A virus strains.

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第一作者： Nikolai Yu,Kuznetsov

第一单位： A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov 28, 119991, Moscow, Russian Federation. nkuznff@ineos.ac.ru.

作者： Nikolai Yu,Kuznetsov ^[1] ; Rabdan M,Tikhov ^[1] ; Ivan A,Godovikov ^[1] ; Michael G,Medvedev ^[1] ; Konstantin A,Lyssenko ^[1] ; Elena I,Burtseva ^[2] ; Elena S,Kirillova ^[2] ; Yuri N,Bubnov ^[3]

作者单位： A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov 28, 119991, Moscow, Russian Federation. nkuznff@ineos.ac.ru. ^[1] N.F. Gamaleya Institute of Epidemiology and Microbiology, Russian Academy of Medicinal Sciences, Gamaleya 18, 123098, Moscow, Russian Federation. ^[2] A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov 28, 119991, Moscow, Russian Federation. nkuznff@ineos.ac.ru and N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky pr. 47, 119991 Moscow, Russian Federation. ^[3]

主题词金刚烷(Adamantane);抗病毒药(Antiviral Agents);抗药性, 病毒(Drug Resistance, Viral);流感病毒A型, H1N1亚型(Influenza A Virus, H1N1 Subtype);金刚乙胺(Rimantadine);立体异构现象(Stereoisomerism)

DOI 10.1039/c7ob00331e

PMID 28338150

发布时间 2018-02-14

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