Characterization of human monoclonal antibodies that neutralize multiple poliovirus serotypes.

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第一作者： Rama Devudu,Puligedda

第一单位： Lankenau Institute for Medical Research, 100 E. Lancaster Ave., Wynnewood, PA 19096, USA.

作者： Rama Devudu,Puligedda ^[1] ; Diana,Kouiavskaia ^[2] ; Fetweh H,Al-Saleem ^[1] ; Chandana Devi,Kattala ^[1] ; Usman,Nabi ^[1] ; Hamid,Yaqoob ^[1] ; V Sandeep,Bhagavathula ^[3] ; Rashmi,Sharma ^[1] ; Konstantin,Chumakov ^[4] ; Scott K,Dessain ^[5]

作者单位： Lankenau Institute for Medical Research, 100 E. Lancaster Ave., Wynnewood, PA 19096, USA. ^[1] Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993, USA. ^[2] Department of Biotechnology, College of Science & Technology, Andhra University, Visakhapatnam 530 003, Andhra Pradesh, India. ^[3] Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993, USA. Electronic address: Konstantin.Chumakov@fda.hhs.gov. ^[4] Lankenau Institute for Medical Research, 100 E. Lancaster Ave., Wynnewood, PA 19096, USA. Electronic address: dessain@limr.org. ^[5]

关键词 Circulating vaccine derived poliovirus (cVDPV)Cross-neutralization Human immunity Immune deficiency associated vaccine derived poliovirus (iVDPV)Monoclonal antibody Neutralization Polio eradication Poliovirus