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首页> Vaccine> Enhancing heterologous protection in pigs vaccinated with chimeric porcine reproductive and respiratory syndrome virus containing the full-length sequences of shuffled structural genes of multiple heterologous strains.

Enhancing heterologous protection in pigs vaccinated with chimeric porcine reproductive and respiratory syndrome virus containing the full-length sequences of shuffled structural genes of multiple heterologous strains.

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第一作者： Debin,Tian

第一单位： Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.

作者： Debin,Tian ^[1] ; Dianjun,Cao ^[1] ; C,Lynn Heffron ^[1] ; Danielle M,Yugo ^[1] ; Adam J,Rogers ^[1] ; Christopher,Overend ^[1] ; Shannon R,Matzinger ^[1] ; Sakthivel,Subramaniam ^[1] ; Tanja,Opriessnig ^[2] ; Tanya,LeRoith ^[1] ; Xiang-Jin,Meng ^[3]

作者单位： Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA. ^[1] Roslin Institute, University of Edinburgh, Midlothian, Scotland, UK. ^[2] Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA. Electronic address: xjmeng@vt.edu. ^[3]

关键词 Cross-protection DNA shuffling Heterologous strains Porcine reproductive and respiratory syndrome virus (PRRSV)RFLP 1-7-4 Vaccine

主题词动物(Animals);交叉保护(Cross Protection);DNA改组(DNA Shuffling);基因, 病毒(Genes, Viral);猪繁殖和呼吸综合征(Porcine Reproductive and Respiratory Syndrome);猪呼吸与生殖综合征病毒(Porcine respiratory and reproductive syndrome virus);猪(Swine);疫苗, 合成(Vaccines, Synthetic);病毒疫苗(Viral Vaccines)

DOI 10.1016/j.vaccine.2017.03.046

PMID 28343773

发布时间 2018-02-07

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