换一批Diallyl trisulfide suppresses tumor growth through the attenuation of Nrf2/Akt and activation of p38/JNK and potentiates cisplatin efficacy in gastric cancer treatment.
第一作者：
Xiao-Yan,Jiang
第一单位：
School of Pharmaceutical Sciences, Shandong University, Ji-nan 250012, China.
作者：
主题词
烯丙化合物(Allyl Compounds);动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);顺铂(Cisplatin);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);女(雌)性(Female);人类(Humans);JNK丝裂原活化蛋白激酶类(JNK Mitogen-Activated Protein Kinases);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);分子结构(Molecular Structure);NF-E2相关因子2(NF-E2-Related Factor 2);肿瘤, 实验性(Neoplasms, Experimental);癌基因蛋白质v-akt(Oncogene Protein v-akt);胃肿瘤(Stomach Neoplasms);构效关系(Structure-Activity Relationship);硫化物(Sulfides);肿瘤细胞, 培养的(Tumor Cells, Cultured);p38丝裂原活化蛋白激酶类(p38 Mitogen-Activated Protein Kinases)
DOI
10.1038/aps.2016.176
PMID
28344324
发布时间
2024-08-02
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Acta pharmacologica Sinica
1048-1058页
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