Biochemical and molecular modulation of CCl<sub>4</sub>-induced peripheral and central damage by <i>Tilia americana</i> var. <i>mexicana</i>extracts.
作者:
关键词
ALB, serum albuminALP, alkaline phosphataseALT, alanine aminotransferaseAST, aspartate aminotransferaseAc.E, ethyl acetate extract groupAntioxidantAq.E, aqueous extract groupAq.E?+?CCl4, aqueous extract-CCl4 groupBACT, β-actinBB, total bilirubinCAT, catalaseCCl3OO?, trichloromethylperoxy radicalCCl4, carbon tetrachlorideCCl4-induced damageCDNB, 1-chloro-2,4-dinitrobenzeneCK, creatine kinaseCOX-2, cyclooxygenaseCREA, creatinineDMPO, 5,5-dimethyl-1-pyrrolin-N-oxideEDTA, ethylenediaminetetraacetic acid disodium saltG6PDH, glucose-6-phosphate dehydrogenaseGAPDH, glyceraldehyde-3 phosphate dehydrogenaseGPx, glutathione peroxidaseGR, glutathione reductaseGSH, reduced form of glutathioneGSSG, oxidized form of glutathioneGST, glutathione-S-transferaseH2O2, hydrogen peroxideHO-1, heme oxygenase-1He.E, hexane extract groupHe.E?+?CCl4, hexane extract-CCl4 groupHepatoprotective effectsMDA, malondialdehydeMe.E, methanol extract groupMe.E?+?CCl4, methanol extract-CCl4 groupNADPH, nicotinamide adenine dinucleotide phosphateNBT, nitro blue tetrazoliumNF-κB, nuclear factor kappa-light-chain-enhancer of activated B cellsNeuroprotective effectsNrf2, nuclear factor erythroid-derived 2-like 2O.O, olive oil groupOxidative stressPPARγ, peroxisome proliferator-activated receptor gammaRNA, ribonucleic acidROS, reactive oxygen speciesSOD, superoxide dismutaseSOD1, superoxide dismutase-1SOD2, superoxide dismutase-1TNF-α, tumor necrosis factorTilia americana var. mexicanaUK, United KingdomUSA, United States of AmericaVar., variant[Formula: see text], trichloromethylbp, base pairi.p., intraperitoneal administrationiNOS, inducible nitric oxide synthaseoxo8-dG, 8-hydroxy-2′-deoxyguanosineγ-GLOB, γ-globulin
DOI
10.1016/j.jsps.2016.06.008
PMID
28344485
发布时间
2023-11-12
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Saudi pharmaceutical journal
2017年25卷3期
319-331页
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