WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel.

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第一作者： Mara,Artibani

第一单位： Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK.

作者： Mara,Artibani ^[1] ; Andrew H,Sims ^[1] ; Joan,Slight ^[1] ; Stuart,Aitken ^[1] ; Anna,Thornburn ^[1] ; Morwenna,Muir ^[1] ; Valerie G,Brunton ^[1] ; Jorge,Del-Pozo ^[2] ; Linda R,Morrison ^[2] ; Elad,Katz ^[1] ; Nicholas D,Hastie ^[1] ; Peter,Hohenstein ^[1]

作者单位： Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK. ^[1] Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK. ^[2] The Roslin Institute, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 9RG, UK. ^[3]

主题词抗肿瘤药(Antineoplastic Agents);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);上皮-间质转化(Epithelial-Mesenchymal Transition);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因敲低技术(Gene Knockdown Techniques);人类(Humans);突变(Mutation);预后(Prognosis);紫杉烷类(Taxoids);增量调节(Up-Regulation);WT1蛋白质类(WT1 Proteins)

DOI 10.1038/srep45255

PMID 28345629

发布时间 2022-01-29

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WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel.

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WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel.

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