Programmed death-ligand 1 and its soluble form are highly expressed in nasal natural killer/T-cell lymphoma: a potential rationale for immunotherapy.

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作者： Toshihiro,Nagato ^[1] ; Takayuki,Ohkuri ^[2] ; Kenzo,Ohara ^[3] ; Yui,Hirata ^[4] ; Kan,Kishibe ^[3] ; Yuki,Komabayashi ^[4] ; Seigo,Ueda ^[3] ; Miki,Takahara ^[4] ; Takumi,Kumai ^[4] ; Kei,Ishibashi ^[4] ; Akemi,Kosaka ^[4] ; Naoko,Aoki ^[4] ; Kensuke,Oikawa ^[3] ; Yuji,Uno ^[3] ; Naoko,Akiyama ^[5] ; Masatoshi,Sado ^[3] ; Hidehiro,Takei ^[3] ; Esteban,Celis ^[3] ; Yasuaki,Harabuchi ^[6] ; Hiroya,Kobayashi ^[6]

作者单位： Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, 078-8510, Japan. rijun@asahikawa-med.ac.jp. ^[1] Department of Pathology, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, 078-8510, Japan. rijun@asahikawa-med.ac.jp. ^[2] Department of Pathology, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, 078-8510, Japan. ^[3] Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, 078-8510, Japan. ^[4] Respiratory and Breast Center, Asahikawa Medical University Hospital, Asahikawa, Japan. ^[5] Department of Surgical Pathology, Asahikawa Medical University Hospital, Asahikawa, Japan. ^[6] Cancer Immunology, Inflammation and Tolerance Program, Georgia Cancer Center, Augusta University, Augusta, GA, USA. ^[7] Department of Pathology, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, 078-8510, Japan. hiroya@asahikawa-med.ac.jp. ^[8]

关键词 Immunotherapy Nasal NK/T-cell lymphoma PD-1 PD-L1 Soluble form