<i>LRRK2</i> but not <i>ATG16L1</i> is associated with Paneth cell defect in Japanese Crohn's disease patients.

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第一作者： Ta-Chiang,Liu

第一单位： Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.

作者： Ta-Chiang,Liu ^[1] ; Takeo,Naito ^[2] ; Zhenqiu,Liu ^[3] ; Kelli L,VanDussen ^[1] ; Talin,Haritunians ^[3] ; Dalin,Li ^[3] ; Katsuya,Endo ^[2] ; Yosuke,Kawai ^[4] ; Masao,Nagasaki ^[4] ; Yoshitaka,Kinouchi ^[5] ; Dermot Pb,McGovern ^[3] ; Tooru,Shimosegawa ^[2] ; Yoichi,Kakuta ^[2] ; Thaddeus S,Stappenbeck ^[1]

作者单位： Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA. ^[1] Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan. ^[2] F. Widjaja Family Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. ^[3] Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan. ^[4] Health Administration Center, Center for the Advancement of Higher Education, Tohoku University, Sendai, Japan. ^[5]

主题词成年人(Adult);自噬(Autophagy);队列研究(Cohort Studies);Crohn病(Crohn Disease);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);人类(Humans);男(雄)性(Male);帕内特细胞(Paneth Cells);多态性, 单核苷酸(Polymorphism, Single Nucleotide);信号传导(Signal Transduction);青年人(Young Adult)

DOI 10.1172/jci.insight.91917

PMID 28352666

发布时间 2020-05-29

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<i>LRRK2</i> but not <i>ATG16L1</i> is associated with Paneth cell defect in Japanese Crohn's disease patients.

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<i>LRRK2</i> but not <i>ATG16L1</i> is associated with Paneth cell defect in Japanese Crohn's disease patients.

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