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DNA methylation mediates genotype and smoking interaction in the development of anti-citrullinated peptide antibody-positive rheumatoid arthritis.

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作者单位: Department of Biochemistry and Molecular Biology, The Ministry of Education Key Laboratory of Metabolism and Molecular Medicine, School of Basic Medical Sciences, Fudan University, West Building 13, 130 Dong An Road, Shanghai, China. [1] State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China. [2] Division of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China. [3] Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. [4] Institute for Medical Research, Jalan Pahang, 50588, Kuala Lumpur, Malaysia. [5] Rheumatology Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. [6] Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany. [7] Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden. [8] Instramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA. [9] Center for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden. [10] Center for Epigenetics and Departments of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. [11] Rheumatology Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. leonid.padyukov@ki.se. [12] Department of Biochemistry and Molecular Biology, The Ministry of Education Key Laboratory of Metabolism and Molecular Medicine, School of Basic Medical Sciences, Fudan University, West Building 13, 130 Dong An Road, Shanghai, China. yliu39@fudan.edu.cn. [13] State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China. yliu39@fudan.edu.cn. [14]
DOI 10.1186/s13075-017-1276-2
PMID 28356135
发布时间 2018-11-13
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Arthritis research & therapy

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