Downregulation of UBC9 promotes apoptosis of activated human LX-2 hepatic stellate cells by suppressing the canonical NF-κB signaling pathway.

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作者： Sufen,Fang ^[1] ; Jinhua,Yuan ^[1] ; Qing,Shi ^[1] ; Tiantian,Xu ^[1] ; Yao,Fu ^[1] ; Zheng,Wu ^[1] ; Wuhua,Guo ^[2]

作者单位： Department of Gastroenterology, Second Affiliated Hospital of Nanchang University, Nanchang, China. ^[1] Department of interventional radiology, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, China. ^[2]

主题词肌动蛋白类(Actins);细胞凋亡(Apoptosis);印迹法, 蛋白质(Blotting, Western);细胞系, 肿瘤(Cell Line, Tumor);胶原Ⅰ型(Collagen Type I);流式细胞术(Flow Cytometry);荧光抗体技术(Fluorescent Antibody Technique);Hep G2细胞(Hep G2 Cells);肝星状细胞(Hepatic Stellate Cells);人类(Humans);NF-κB(NF-kappa B);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);泛素缀合酶类(Ubiquitin-Conjugating Enzymes)

DOI 10.1371/journal.pone.0174374

PMID 28358817

发布时间 2018-11-13

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2017年12卷3期

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Downregulation of UBC9 promotes apoptosis of activated human LX-2 hepatic stellate cells by suppressing the canonical NF-κB signaling pathway.

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Downregulation of UBC9 promotes apoptosis of activated human LX-2 hepatic stellate cells by suppressing the canonical NF-κB signaling pathway.

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