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Synthesis, stability and mechanistic studies of potent anticryptococcal hexapeptides.

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第一作者： Kitika,Shenmar

第一单位： Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab, 160 062, India.

作者： Kitika,Shenmar ^[1] ; Krishna K,Sharma ^[1] ; Nishima,Wangoo ^[2] ; Indresh K,Maurya ^[3] ; Vinod,Kumar ^[4] ; Shabana I,Khan ^[5] ; Melissa R,Jacob ^[5] ; Kulbhushan,Tikoo ^[4] ; Rahul,Jain ^[6]

作者单位： Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab, 160 062, India. ^[1] Department of Applied Sciences, University Institute of Engineering and Technology (U.I.E.T.), Panjab University, Sector-25, Chandigarh, 160014, India. ^[2] Department of Microbial Biotechnology, Panjab University, Sector-14, Chandigarh, 160014, India. ^[3] Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab, 160 062, India. ^[4] National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677, USA. ^[5] Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab, 160 062, India. Electronic address: rahuljain@niper.ac.in. ^[6]

关键词 Amphiphilic hexapeptides Anticryptococcal Electron microscopy Proteolysis Solid phase peptide synthesis