Population pharmacokinetics analysis of VRC01, an HIV-1 broadly neutralizing monoclonal antibody, in healthy adults.

导出 OA

翻译打印收藏纠错

作者： Yunda,Huang ^[1] ; Lily,Zhang ^[2] ; Julie,Ledgerwood ^[3] ; Nicole,Grunenberg ^[4] ; Robert,Bailer ^[3] ; Abby,Isaacs ^[5] ; Kelly,Seaton ^[3] ; Kenneth H,Mayer ^[6] ; Edmund,Capparelli ^[7] ; Larry,Corey ^[8] ; Peter B,Gilbert ^[3]

作者单位： a Vaccine and Infectious Disease Division, Public Health Division , Fred Hutchinson Cancer Research Center , Seattle , WA , USA. ^[1] b Department of Global Health , University of Washington , Seattle , WA , USA. ^[2] c Vaccine And Infectious Disease Division , Fred Hutchinson Cancer Research Center , Seattle , WA , USA. ^[3] d Vaccine Research Center, National Institute of Allergy and Infectious Diseases , Bethesda , MD , USA. ^[4] e Vaccine Research Center, National Institute of Allergy and Infectious Diseases , Bethesda , MD , USA. ^[5] f Duke Human Vaccine Institute, Duke University Medical Center , Durham , NC , USA. ^[6] g The Fenway Institute , Boston , MA , USA. ^[7] h University of California , San Diego , CA , USA. ^[8] i Department of Biostatistics , University of Washington , Seattle , WA , USA. ^[9]

关键词 Body weight VRC01 serum concentration multiple-dose time-concentration curve two-compartment