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Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.

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第一作者： Akane,Kawamura

第一单位： Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK.;Division of Cardiovascular Medicine, Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.

作者： Akane,Kawamura ^[1] ; Martin,Münzel ^[2] ; Tatsuya,Kojima ^[3] ; Clarence,Yapp ^[4] ; Bhaskar,Bhushan ^[1] ; Yuki,Goto ^[3] ; Anthony,Tumber ^[4] ; Takayuki,Katoh ^[3] ; Oliver N F,King ^[2] ; Toby,Passioura ^[3] ; Louise J,Walport ^[2] ; Stephanie B,Hatch ^[4] ; Sarah,Madden ^[2] ; Susanne,Müller ^[4] ; Paul E,Brennan ^[4] ; Rasheduzzaman,Chowdhury ^[2] ; Richard J,Hopkinson ^[2] ; Hiroaki,Suga ^[5] ; Christopher J,Schofield ^[2]

作者单位： Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK.;Division of Cardiovascular Medicine, Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK. ^[1] Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK. ^[2] Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan. ^[3] Structural Genomics Consortium, University of Oxford, Old Road Campus Roosevelt Drive, Headington OX3 7DQ, UK.;Nuffield Department of Medicine, Target Discovery Institute, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK. ^[4] Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan.;JST, CREST, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-0033, Japan. ^[5]