换一批
换一批The design of novel inhibitors for treating cancer by targeting CDC25B through disruption of CDC25B-CDK2/Cyclin A interaction using computational approaches.
第一作者：
Hong-Lian,Li
第一单位：
Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, China.
作者：
主题词
抗肿瘤药(Antineoplastic Agents);结合部位(Binding Sites);细胞周期蛋白A(Cyclin A);细胞周期蛋白依赖激酶2(Cyclin-Dependent Kinase 2);药物设计(Drug Design);酶抑制剂(Enzyme Inhibitors);人类(Humans);氢键合(Hydrogen Bonding);模型, 分子(Models, Molecular);分子构象(Molecular Conformation);分子动力学模拟(Molecular Dynamics Simulation);多蛋白复合物(Multiprotein Complexes);蛋白质结合(Protein Binding);构效关系(Structure-Activity Relationship);cdc25磷酸酶类(cdc25 Phosphatases)
DOI
10.18632/oncotarget.16600
PMID
28402259
发布时间
2018-11-13
- 浏览23
Oncotarget
33225-33240页
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