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The Use of a Binary Composite Endpoint and Sample Size Requirement: Influence of Endpoints Overlap.

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第一作者： Josep-Ramon,Marsal

第一单位： Epidemiology Unit, Department of Cardiology, Vall d'Hebron Hospital, Passeig de la Vall d'Hebron, Barcelona, Spain.;Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain;Department of Pediatrics, Obstetrics and Gynecology and Public Health of Universitat Autònoma de Barcelona, Cerdanyola del Vallés, Spain;Unit of Research Support, Primary Care Research Institute (IDIAP) Jordi Gol, Catalan Institute of Health, Lleida, Spain

作者： Josep-Ramon,Marsal ^[1] ; Ignacio,Ferreira-González ^[2] ; Sandra,Bertran ^[3] ; Aida,Ribera ^[2] ; Gaietà,Permanyer-Miralda ^[2] ; David,García-Dorado ^[2] ; Guadalupe,Gómez ^[4]

作者单位： Epidemiology Unit, Department of Cardiology, Vall d'Hebron Hospital, Passeig de la Vall d'Hebron, Barcelona, Spain.;Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain;Department of Pediatrics, Obstetrics and Gynecology and Public Health of Universitat Autònoma de Barcelona, Cerdanyola del Vallés, Spain;Unit of Research Support, Primary Care Research Institute (IDIAP) Jordi Gol, Catalan Institute of Health, Lleida, Spain ^[1] Epidemiology Unit, Department of Cardiology, Vall d'Hebron Hospital, Passeig de la Vall d'Hebron, Barcelona, Spain.;Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain ^[2] Epidemiology Unit, Department of Cardiology, Vall d'Hebron Hospital, Passeig de la Vall d'Hebron, Barcelona, Spain.;Department of Statistics and Operations Research, Universitat Politècnica de Catalunya, Barcelona, Spain ^[3] Department of Statistics and Operations Research, Universitat Politècnica de Catalunya, Barcelona, Spain ^[4]

关键词 association measures binary endpoints composite endpoint correlated endpoints outcome assessment sample size

医学主题词流行病学方法(Epidemiologic Methods);流行病学研究(Epidemiologic Studies);人类(Humans);样本大小(Sample Size)

DOI 10.1093/aje/kww105

PMID 28402501

发布时间 2019-06-17

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