Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity.

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第一作者： Wenqian,Dong

第一单位： Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing, China.

作者： Wenqian,Dong ^[1] ; Huafeng,Zhang ^[2] ; Xiaonan,Yin ^[1] ; Yuying,Liu ^[3] ; Degao,Chen ^[1] ; Xiaoyu,Liang ^[1] ; Xun,Jin ^[1] ; Jiadi,Lv ^[1] ; Jingwei,Ma ^[2] ; Ke,Tang ^[2] ; Zhuowei,Hu ^[4] ; Xiaofeng,Qin ^[5] ; Bo,Huang ^[6]

作者单位： Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing, China. ^[1] Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology , Wuhan, China. ^[2] Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing, China. ^[3] Molecular Immunology and Pharmacology Group, State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing, China. ^[4] Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Suzhou Institute of Systems Medicine, Suzhou, China. ^[5] Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China; Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing, China. ^[6]

关键词 Antitumor immunity NOD2 signaling intestinal epithelial cells oral vaccines tumor microparticles

DOI 10.1080/2162402X.2017.1282589

PMID 28405506

发布时间 2021-01-12

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Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity.

Oncoimmunology

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Oncoimmunology

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Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity.

Oncoimmunology

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Oncoimmunology

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