Improved release of triamcinolone acetonide from medicated soft contact lenses loaded with drug nanosuspensions.

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作者： Eva,García-Millán ^[1] ; Mónica,Quintáns-Carballo ^[1] ; Francisco Javier,Otero-Espinar ^[2]

作者单位： Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Santiago de Compostela, Campus Vida s/n, 15782, Santiago de Compostela, Spain. ^[1] Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Santiago de Compostela, Campus Vida s/n, 15782, Santiago de Compostela, Spain; Instituto de Farmacia Industrial, Facultad de Farmacia, Universidad de Santiago de Compostela, Campus Vida s/n, 15782, Santiago de Compostela, Spain. Electronic address: francisco.otero@usc.es. ^[2]

关键词 2,2′-Azo-bis(isobutyronitrile) AIBN (CID 6547)2-Hydroxyethyl methacrylate HEMA (CID 13360)Ethyleneglycol dimethacrylate EGDMA (CID:7355) Poloxamer 407 Medicated soft contact lenses Methacrylic acid MA (CID: 4093)Nanosuspensions Ocular Ocular drug release Polyvinyl alcohol PVA (CID 11199)Triamcinolone Acetonide TA (CID: 6436)Triamcinolone acetonide pHEMA hydrogels

主题词接触镜, 亲水性(Contact Lenses, Hydrophilic);药物释放系统(Drug Delivery Systems);水凝胶类(Hydrogels);甲基丙烯酸盐(Methacrylates);曲安奈德(Triamcinolone Acetonide)

DOI 10.1016/j.ijpharm.2017.03.082

PMID 28412447

发布时间 2018-12-02

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