SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein.
第一作者:
C,Geng
第一单位:
Department of Medicine, Baylor College of Medicine, Houston, TX, USA.;Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
作者:
医学主题词
腺癌(Adenocarcinoma);动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);队列研究(Cohort Studies);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);突变(Mutation);核蛋白质类(Nuclear Proteins);前列腺(Prostate);前列腺上皮内瘤病(Prostatic Intraepithelial Neoplasia);前列腺肿瘤(Prostatic Neoplasms);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);受体, 雄激素(Receptors, Androgen);阻遏蛋白质类(Repressor Proteins);泛素蛋白连接酶复合物(Ubiquitin-Protein Ligase Complexes);泛素化(Ubiquitination)
DOI
10.1038/onc.2017.80
PMID
28414305
发布时间
2024-06-10
- 浏览15
Oncogene
4767-4777页
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