首页> Clinical cancer research : an official journal of the American Association for Cancer Research> A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors.

A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors.

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第一作者： Birgit,Geoerger

第一单位： Department of Pediatric and Adolescent Oncology, Gustave Roussy and UMR 8203, CNRS, Univ. Paris-Sud, Villejuif, France. birgit.geoerger@gustaveroussy.fr.

作者： Birgit,Geoerger ^[1] ; Franck,Bourdeaut ^[2] ; Steven G,DuBois ^[3] ; Matthias,Fischer ^[4] ; James I,Geller ^[5] ; Nicholas G,Gottardo ^[6] ; Aurélien,Marabelle ^[7] ; Andrew D J,Pearson ^[8] ; Shakeel,Modak ^[9] ; Thomas,Cash ^[10] ; Giles W,Robinson ^[11] ; Marlyane,Motta ^[12] ; Alessandro,Matano ^[13] ; Suraj G,Bhansali ^[14] ; Jason R,Dobson ^[12] ; Sudha,Parasuraman ^[12] ; Susan N,Chi ^[15]

作者单位： Department of Pediatric and Adolescent Oncology, Gustave Roussy and UMR 8203, CNRS, Univ. Paris-Sud, Villejuif, France. birgit.geoerger@gustaveroussy.fr. ^[1] Institut Curie, PSL Research University, Department of Pediatric Oncology and INSERM U830, Paris, France. ^[2] Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston, Massachusetts. ^[3] Department of Pediatric Oncology and Hematology, University Children's Hospital of Cologne, Medical Faculty and Center for Molecular Medicine Cologne (CMMC), University of Cologne; Max Planck Institute for Metabolism Research, Cologne, Germany. ^[4] UC Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio. ^[5] Princess Margaret Hospital for Children, Perth, Western Australia, Australia. ^[6] Institute for Pediatric HematoOncology, Léon Bérard Cancer Center, Lyon, France. ^[7] The Royal Marsden NHS Foundation Trust & Institute of Cancer Research, The Royal Marsden Hospital, Sutton, United Kingdom (Retired). ^[8] Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York. ^[9] Department of Pediatrics, Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia. ^[10] Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee. ^[11] Translational Clinical Oncology, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts. ^[12] Translational Clinical Oncology, Novartis Pharma AG, Basel, Switzerland. ^[13] Clinical Pharmacology, Translational Clinical Oncology, Novartis Institutes for BioMedical Research, East Hanover, New Jersey. ^[14] Pediatric NeuroOncology, DanaFarber Cancer Institute, Boston, Massachusetts. ^[15]