Formulation, release characteristics, and bioavailability study of gastroretentive floating matrix tablet and floating raft system of Mebeverine HCl.

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作者： Mohamed A,El Nabarawi ^[1] ; Mahmoud H,Teaima ^[1] ; Rehab A,Abd El-Monem ^[2] ; Nagla A,El Nabarawy ^[3] ; Dalia A,Gaber ^[4]

作者单位： Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt. ^[1] Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Misr University for Science and Technology, 6th of October, Egypt. ^[2] National Egyptian Center of Environment and Toxicological Research (NECTER), Faculty of Medicine, Cairo University, Cairo, Egypt. ^[3] Department of Quality Control, Holding Company for Biological Products and Vaccines, Cairo, Egypt. ^[4]

关键词 Compritol?GRDDS HPMC Na alginate Precirol?

主题词投药, 口服(Administration, Oral);动物(Animals);生物利用度(Biological Availability);迟效制剂(Delayed-Action Preparations);狗(Dogs);药物调剂(Drug Compounding);胃黏膜(Gastric Mucosa);男(雄)性(Male);苯乙胺类(Phenethylamines);片剂(Tablets)

DOI 10.2147/DDDT.S131936

PMID 28435220

发布时间 2018-12-02

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Drug design, development and therapy

2017年11卷

1081-1093页

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Formulation, release characteristics, and bioavailability study of gastroretentive floating matrix tablet and floating raft system of Mebeverine HCl.

Drug design, development and therapy

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Drug design, development and therapy

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Formulation, release characteristics, and bioavailability study of gastroretentive floating matrix tablet and floating raft system of Mebeverine HCl.

Drug design, development and therapy

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Drug design, development and therapy

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