换一批
换一批Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
作者：
Felix R,Day [1]
;
Deborah J,Thompson [2]
;
Hannes,Helgason [3]
;
Daniel I,Chasman [4]
;
Hilary,Finucane [5]
;
Patrick,Sulem [6]
;
Katherine S,Ruth [7]
;
Sean,Whalen [8]
;
Abhishek K,Sarkar [3]
;
Eva,Albrecht [9]
;
Elisabeth,Altmaier [10]
;
Marzyeh,Amini [11]
;
Caterina M,Barbieri [12]
;
Thibaud,Boutin [13]
;
Archie,Campbell [14]
;
Ellen,Demerath [15]
;
Ayush,Giri [16]
;
Chunyan,He [17]
;
Jouke J,Hottenga [18]
;
Robert,Karlsson [19]
;
Ivana,Kolcic [20]
;
Po-Ru,Loh [21]
;
Kathryn L,Lunetta [22]
;
Massimo,Mangino [23]
;
Brumat,Marco [24]
;
George,McMahon [25]
;
Sarah E,Medland [26]
;
Ilja M,Nolte [27]
;
Raymond,Noordam [7]
;
Teresa,Nutile [28]
;
Lavinia,Paternoster [29]
;
Natalia,Perjakova [30]
;
Eleonora,Porcu [31]
;
Lynda M,Rose [32]
;
Katharina E,Schraut [33]
;
Ayellet V,Segrè [34]
;
Albert V,Smith [35]
;
Lisette,Stolk [16]
;
Alexander,Teumer [36]
;
Irene L,Andrulis [37]
;
Stefania,Bandinelli [34]
;
Matthias W,Beckmann [38]
;
Javier,Benitez [39]
;
Sven,Bergmann [40]
;
Murielle,Bochud [5]
;
Eric,Boerwinkle [41]
;
Stig E,Bojesen [42]
;
Manjeet K,Bolla [43]
;
Judith S,Brand [44]
;
Hiltrud,Brauch [45]
;
Hermann,Brenner [46]
;
Linda,Broer [47]
;
Thomas,Brüning [48]
;
Julie E,Buring [49]
;
Harry,Campbell [50]
;
Eulalia,Catamo [51]
;
Stephen,Chanock [52]
;
Georgia,Chenevix-Trench [53]
;
Tanguy,Corre [54]
;
Fergus J,Couch [55]
;
Diana L,Cousminer [56]
;
Angela,Cox [57]
;
Laura,Crisponi [58]
;
Kamila,Czene [59]
;
George,Davey Smith [60]
;
Eco J C N,de Geus [2]
;
Renée,de Mutsert [26]
;
Immaculata,De Vivo [61]
;
Joe,Dennis [62]
;
Peter,Devilee [63]
;
Isabel,Dos-Santos-Silva [63]
;
Alison M,Dunning [64]
;
Johan G,Eriksson [65]
;
Peter A,Fasching [46]
;
Lindsay,Fernández-Rhodes [66]
;
Luigi,Ferrucci [5]
;
Dieter,Flesch-Janys [6]
;
Lude,Franke [42]
;
Marike,Gabrielson [67]
;
Ilaria,Gandin [68]
;
Graham G,Giles [69]
;
Harald,Grallert [54]
;
Daniel F,Gudbjartsson [55]
;
Pascal,Guénel [56]
;
Per,Hall [70]
;
Emily,Hallberg [71]
;
Ute,Hamann [72]
;
Tamara B,Harris [73]
;
Catharina A,Hartman [40]
;
Gerardo,Heiss [26]
;
Maartje J,Hooning [34]
;
John L,Hopper [38]
;
Frank,Hu [25]
;
David J,Hunter [74]
;
M Arfan,Ikram [7]
;
Hae Kyung,Im [75]
;
Marjo-Riitta,Järvelin [2]
;
Peter K,Joshi [76]
;
David,Karasik [77]
;
Manolis,Kellis [78]
;
Zoltan,Kutalik [79]
;
Genevieve,LaChance [80]
;
Diether,Lambrechts [51]
;
Claudia,Langenberg [81]
;
Lenore J,Launer [82]
;
Joop S E,Laven [83]
;
Stefania,Lenarduzzi [84]
;
Jingmei,Li [85]
;
Penelope A,Lind [86]
;
Sara,Lindstrom [26]
;
YongMei,Liu [33]
;
Jian'an,Luan [87]
;
Reedik,Mägi [88]
;
Arto,Mannermaa [14]
;
Hamdi,Mbarek [15]
;
Mark I,McCarthy [89]
;
Christa,Meisinger [3]
;
Thomas,Meitinger [4]
;
Cristina,Menni [90]
;
Andres,Metspalu [26]
;
Kyriaki,Michailidou [91]
;
Lili,Milani [92]
;
Roger L,Milne [93]
;
Grant W,Montgomery [94]
;
Anna M,Mulligan [82]
;
Mike A,Nalls [95]
;
Pau,Navarro [88]
;
Heli,Nevanlinna [75]
;
Dale R,Nyholt [96]
;
Albertine J,Oldehinkel [7]
;
Tracy A,O'Mara [75]
;
Sandosh,Padmanabhan [96]
;
Aarno,Palotie [97]
;
Nancy,Pedersen [98]
;
Annette,Peters [99]
;
Julian,Peto [100]
;
Paul D P,Pharoah [101]
;
Anneli,Pouta [102]
;
Paolo,Radice [103]
;
Iffat,Rahman [42]
;
Susan M,Ring [6]
;
Antonietta,Robino [104]
;
Frits R,Rosendaal [11]
;
Igor,Rudan [12]
;
Rico,Rueedi [54]
;
Daniela,Ruggiero [56]
;
Cinzia F,Sala [31]
;
Marjanka K,Schmidt [105]
;
Robert A,Scott [106]
;
Mitul,Shah [1]
;
Rossella,Sorice [93]
;
Melissa C,Southey [107]
;
Ulla,Sovio [67]
;
Meir,Stampfer [26]
;
Maristella,Steri [35]
;
Konstantin,Strauch [108]
;
Toshiko,Tanaka [109]
;
Emmi,Tikkanen [1]
;
Nicholas J,Timpson [39]
;
Michela,Traglia [110]
;
Thérèse,Truong [111]
;
Jonathan P,Tyrer [112]
;
André G,Uitterlinden [25]
;
Digna R Velez,Edwards [113]
;
Veronique,Vitart [114]
;
Uwe,Völker [115]
;
Peter,Vollenweider [14]
;
Qin,Wang [116]
;
Elisabeth,Widen [117]
;
Ko Willems,van Dijk [31]
;
Gonneke,Willemsen [39]
;
Robert,Winqvist [2]
;
Bruce H R,Wolffenbuttel [118]
;
Jing Hua,Zhao [39]
;
Magdalena,Zoledziewska [87]
;
Marek,Zygmunt [88]
;
Behrooz Z,Alizadeh [119]
;
Dorret I,Boomsma [120]
;
Marina,Ciullo [121]
;
Francesco,Cucca [122]
;
Tõnu,Esko [18]
;
Nora,Franceschini [123]
;
Christian,Gieger [124]
;
Vilmundur,Gudnason [125]
;
Caroline,Hayward [69]
;
Peter,Kraft [126]
;
Debbie A,Lawlor [28]
;
Patrik K E,Magnusson [127]
;
Nicholas G,Martin [128]
;
Dennis O,Mook-Kanamori [129]
;
Ellen A,Nohr [130]
;
Ozren,Polasek [131]
;
David,Porteous [26]
;
Alkes L,Price [14]
;
Paul M,Ridker [89]
;
Harold,Snieder [78]
;
Tim D,Spector [2]
;
Doris,Stöckl [79]
;
Daniela,Toniolo [132]
;
Sheila,Ulivi [133]
;
Jenny A,Visser [134]
;
Henry,Völzke [34]
;
Nicholas J,Wareham [38]
;
James F,Wilson [67]
;
LifeLines Cohort Study [74]
;
InterAct Consortium [42]
;
kConFab/AOCS Investigators [54]
;
Endometrial Cancer Association Consortium [55]
;
Ovarian Cancer Association Consortium [37]
;
PRACTICAL consortium [17]
;
Amanda B,Spurdle [135]
;
Unnur,Thorsteindottir [136]
;
Katherine S,Pollard [1]
;
Douglas F,Easton [79]
;
Joyce Y,Tung [37]
;
Jenny,Chang-Claude [137]
;
David,Hinds [99]
;
Anna,Murray [138]
;
Joanne M,Murabito [7]
;
Kari,Stefansson [75]
;
Ken K,Ong [40]
;
John R B,Perry [13]
作者单位：
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.
[1]
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
[2]
deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
[3]
School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
[4]
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
[5]
Harvard Medical School, Boston, Massachusetts, USA.
[6]
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.
[7]
Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
[8]
Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.
[9]
Gladstone Institutes, San Francisco, California, USA.
[10]
Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
[11]
Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
[12]
Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
[13]
Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
[14]
Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
[15]
Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
[16]
Genetics of Common Disorders Unit, IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Milan, Italy.
[17]
Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
[18]
Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
[19]
Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
[20]
Division of Epidemiology, Institute for Medicine and Public Health, Vanderbilt University, Nashville, Tennessee, USA.
[21]
Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.
[22]
Department of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, Indiana, USA.
[23]
Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, USA.
[24]
Department of Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands.
[25]
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
[26]
Faculty of Medicine, University of Split, Split, Croatia.
[27]
Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.
[28]
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
[29]
NHLBI's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.
[30]
Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
[31]
National Institute for Health Research (NIHR) Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK.
[32]
Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, Trieste, Italy.
[33]
School of Social and Community Medicine, University of Bristol, Bristol, UK.
[34]
QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
[35]
Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
[36]
Institute of Genetics and Biophysics, CNR, Naples, Italy.
[37]
MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
[38]
Estonian Genome Center, University of Tartu, Tartu, Estonia.
[39]
Institute of Genetics and Biomedical Research, National Research Council, Cagliari, Italy.
[40]
Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK.
[41]
Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
[42]
Cancer Program, Broad Institute, Cambridge, Massachusetts, USA.
[43]
Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
[44]
Icelandic Heart Association, Kopavogur, Iceland.
[45]
Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands.
[46]
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
[47]
Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.
[48]
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
[49]
Geriatric Unit, Azienda Sanitaria di Firenze, Florence, Italy.
[50]
Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany.
[51]
Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
[52]
Centro de Investigación en Red de Enfermedades Raras (CIBERER), Valencia, Spain.
[53]
Swiss Institute of Bioinformatics, Lausanne, Switzerland.
[54]
Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
[55]
Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland.
[56]
Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, USA.
[57]
Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark.
[58]
Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark.
[59]
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
[60]
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.
[61]
University of Tübingen, Tübingen, Germany.
[62]
German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[63]
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[64]
Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
[65]
Institute for Prevention and Occupational Medicine of German Social Accident Insurance, Institute of Ruhr University Bochum (IPA), Bochum, Germany.
[66]
Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy.
[67]
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
[68]
Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
[69]
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
[70]
Division of Genetics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
[71]
Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
[72]
Academic Unit of Molecular Oncology, Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
[73]
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
[74]
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
[75]
Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.
[76]
Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.
[77]
Non-Communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK.
[78]
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
[79]
Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.
[80]
David Geffen School of Medicine, Department of Medicine, Division of Hematology and Oncology, University of California at Los Angeles, Los Angles, California, USA.
[81]
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA.
[82]
Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, USA.
[83]
Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany.
[84]
Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf, Hamburg, Germany.
[85]
Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
[86]
Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia.
[87]
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
[88]
German Center for Diabetes Research, Neuherberg, Germany.
[89]
Cancer and Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France.
[90]
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
[91]
Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
[92]
Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, Maryland, USA.
[93]
Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
[94]
Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
[95]
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.
[96]
Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
[97]
Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
[98]
Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
[99]
Biocenter Oulu, University of Oulu, Oulu, Finland.
[100]
Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland.
[101]
Institute of Health Sciences, University of Oulu, Oulu, Finland.
[102]
Unit of Primary Care, Oulu University Hospital, Oulu, Finland.
[103]
Hebrew SeniorLife Institute for Aging Research, Boston, Massachusetts, USA.
[104]
Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium.
[105]
Vesalius Research Center (VRC), VIB, Leuven, Belgium.
[106]
Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus MC, Rotterdam, the Netherlands.
[107]
Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, USA.
[108]
Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
[109]
Translational Cancer Research Area, University of Eastern Finland, Kuopio, Finland.
[110]
Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland.
[111]
Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland.
[112]
NIHR Oxford Biomedical Research Centre, Churchill Hospital, Oxford, UK.
[113]
Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK.
[114]
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
[115]
Central Hospital of Augsburg, MONICA/KORA Myocardial Infarction Registry, Augsburg, Germany.
[116]
Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
[117]
Department of Electron Microscopy/Molecular Pathology, Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
[118]
Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
[119]
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
[120]
Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.
[121]
Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
[122]
Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
[123]
Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
[124]
Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
[125]
British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
[126]
Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
[127]
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
[128]
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
[129]
Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
[130]
Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
[131]
National Institute for Health and Welfare, Helsinki, Finland.
[132]
Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy.
[133]
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
[134]
Division of Molecular Pathology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
[135]
Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
[136]
Department of Pathology, University of Melbourne, Melbourne, Victoria, Australia.
[137]
Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK.
[138]
Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.
[139]
Department of Public Health, University of Helsinki, Helsinki, Finland.
[140]
Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt University, Nashville, Tennessee, USA.
[141]
Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
[142]
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
[143]
University Hospital of Lausanne, Lausanne, Switzerland.
[144]
Department of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands.
[145]
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands.
[146]
Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu, Oulu, Finland.
[147]
Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland.
[148]
Department of Endocrinology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
[149]
Department of Obstetrics and Gynecology, University Medicine Greifswald, Greifswald, Germany.
[150]
Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
[151]
Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA.
[152]
Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.
[153]
Research Unit for Gynaecology and Obstetrics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
[154]
Department of Obstetrics and Gynaecology, Campus Grosshadern, Ludwig Maximilians University, Munich, Germany.
[155]
Division of Biostatistics, Institute for Human Genetics, and Institute for Computational Health Sciences, University of California, San Francisco, San Francisco, California, USA.
[156]
23andMe, Inc., Mountain View, California, USA.
[157]
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[158]
University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[159]
Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, Massachusetts, USA.
[160]
Department of Paediatrics, University of Cambridge, Cambridge, UK.
[161]
主题词
青少年(Adolescent);年龄因素(Age Factors);人体质量指数(Body Mass Index);钙结合蛋白质类(Calcium-Binding Proteins);数据库, 遗传学(Databases, Genetic);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);基因组印迹(Genomic Imprinting);人类(Humans);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);男(雄)性(Male);膜蛋白质类(Membrane Proteins);月经初潮(Menarche);肿瘤(Neoplasms);多态性, 单核苷酸(Polymorphism, Single Nucleotide);青春期(Puberty);数量性状基因座位(Quantitative Trait Loci);核糖核蛋白类(Ribonucleoproteins);危险因素(Risk Factors);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)
DOI
10.1038/ng.3841
PMID
28436984
发布时间
2024-03-14
- 浏览10
Nature genetics
Nature genetics
834-841页
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