作者：
Ly P,Vu [1]
;
Camila,Prieto [1]
;
Elianna M,Amin [2]
;
Sagar,Chhangawala [1]
;
Andrei,Krivtsov [2]
;
M Nieves,Calvo-Vidal [3]
;
Timothy,Chou [4]
;
Arthur,Chow [5]
;
Gerard,Minuesa [6]
;
Sun Mi,Park [1]
;
Trevor S,Barlowe [1]
;
James,Taggart [1]
;
Patrick,Tivnan [1]
;
Raquel P,Deering [1]
;
Lisa P,Chu [1]
;
Jeong-Ah,Kwon [1]
;
Cem,Meydan [7]
;
Javier,Perales-Paton [8]
;
Arora,Arshi [9]
;
Mithat,Gönen [10]
;
Christopher,Famulare [11]
;
Minal,Patel [12]
;
Elisabeth,Paietta [12]
;
Martin S,Tallman [13]
;
Yuheng,Lu [13]
;
Jacob,Glass [14]
;
Francine E,Garret-Bakelman [15]
;
Ari,Melnick [3]
;
Ross,Levine [15]
;
Fatima,Al-Shahrour [16]
;
Marcus,Järås [17]
;
Nir,Hacohen [17]
;
Alexia,Hwang [13]
;
Ralph,Garippa [11]
;
Christopher J,Lengner [18]
;
Scott A,Armstrong [7]
;
Leandro,Cerchietti [19]
;
Glenn S,Cowley [19]
;
David,Root [20]
;
John,Doench [4]
;
Christina,Leslie [5]
;
Benjamin L,Ebert [5]
;
Michael G,Kharas [21]
作者单位：
Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, and Center for Experimental Therapeutics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[1]
Physiology, Biophysics and Systems Biology Graduate Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York, USA.
[2]
Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[3]
Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[4]
Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
[5]
Department of Medicine, Division of Hematology/Oncology, Weill Cornell Medical College, New York, New York, USA.
[6]
Harvard Medical School, Boston, Massachusetts, USA.
[7]
Division of Hematology, Brigham and Woman's Hospital, Boston, Massachusetts, USA.
[8]
Whitehead Institute, Boston, Massachusetts, USA.
[9]
Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York, USA.
[10]
Translational Bioinformatics Unit, Clinical Research Programme, Spanish National Cancer Research Centre, Madrid, Spain.
[11]
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[12]
Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[13]
Department of Medicine, Montefiore Medical Center, Bronx, New York, USA.
[14]
Leukemia Service, Department of Medicine, Memorial Sloan Kettering Hospital, New York, New York, USA.
[15]
Department of Medicine and Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA.
[16]
Division of Hematology and Medical Oncology, Departments of Medicine and Pharmacology, Weill Cornell Medical College, Cornell University, New York, New York, USA.
[17]
Department of Clinical Genetics, Lund University, Lund, Sweden.
[18]
RNAi Core, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[19]
Department of Animal Biology, Department of Cell and Developmental Biology, and Institute for Regenerative Medicine, Schools of Veterinary Medicine and Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
[20]
Discovery Sciences, Janssen Research and Development, Spring House, Pennsylvania, USA.
[21]
Broad Institute, Boston, Massachusetts, USA.
[22]
主题词
动物(Animals);细胞存活(Cell Survival);女(雌)性(Female);基因表达调控, 白血病(Gene Expression Regulation, Leukemic);血细胞生成(Hematopoiesis);核不均一核糖核蛋白类(Heterogeneous-Nuclear Ribonucleoproteins);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);白血病, 双表型, 急性(Leukemia, Biphenotypic, Acute);白血病, 髓样(Leukemia, Myeloid);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);骨髓祖代细胞(Myeloid Progenitor Cells);RNA, 小分子干扰(RNA, Small Interfering);RNA结合蛋白质类(RNA-Binding Proteins);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1038/ng.3854
PMID
28436985
发布时间
2021-02-06
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