A murine preclinical syngeneic transplantation model for breast cancer precision medicine.

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第一作者： Lorenzo,Federico

第一单位： Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

作者： Lorenzo,Federico ^[1] ; Zechen,Chong ^[2] ; Dong,Zhang ^[1] ; Daniel J,McGrail ^[1] ; Wei,Zhao ^[1] ; Kang Jin,Jeong ^[1] ; Christopher P,Vellano ^[1] ; Zhenlin,Ju ^[1] ; Mihai,Gagea ^[3] ; Shuying,Liu ^[4] ; Shreya,Mitra ^[1] ; Jennifer B,Dennison ^[1] ; Philip L,Lorenzi ^[2] ; Robert,Cardnell ^[5] ; Lixia,Diao ^[2] ; Jing,Wang ^[2] ; Yiling,Lu ^[1] ; Lauren A,Byers ^[5] ; Charles M,Perou ^[6] ; Shiaw-Yih,Lin ^[1] ; Gordon B,Mills ^[1]

作者单位： Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[1] Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA. ^[2] Department of Veterinary Medicine and Surgery, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[3] Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA. ^[4] Department of Thoracic Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[5] Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA. ^[6]

关键词 Biomarkers PARP1 animal models breast cancer lysophospholipids personalized medicine targeted therapy

主题词动物(Animals);女(雌)性(Female);人类(Humans);MAP激酶信号系统(MAP Kinase Signaling System);乳房肿瘤, 实验性(Mammary Neoplasms, Experimental);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);肿瘤蛋白质类(Neoplasm Proteins);肿瘤移植(Neoplasm Transplantation);酞嗪类(Phthalazines);移植, 同基因(Transplantation, Isogeneic)

DOI 10.1126/sciadv.1600957

PMID 28439535

发布时间 2018-11-13

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Science advances

2017年3卷4期

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A murine preclinical syngeneic transplantation model for breast cancer precision medicine.

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A murine preclinical syngeneic transplantation model for breast cancer precision medicine.

Science advances

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