Studies on the metabolites difference of psoralen/isopsoralen in human and six mammalian liver microsomes in vitro by UHPLC-MS/MS.

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第一作者： Aihong,Yang

第一单位： School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, PR China; Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin, 300193, PR China.

作者： Aihong,Yang ^[1] ; Junxiu,Chen ^[2] ; Yetao,Ma ^[2] ; Lili,Wang ^[1] ; Yaowen,Fan ^[2] ; Xin,He ^[3]

作者单位： School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, PR China; Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin, 300193, PR China. ^[1] School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, PR China. ^[2] School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, PR China; Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin, 300193, PR China. Electronic address: hexintn@163.com. ^[3]

关键词 Epoxide Isopsoralen Metabolism Psoralen Species difference

主题词动物(Animals);色谱法, 高压液相(Chromatography, High Pressure Liquid);呋喃并香豆素(Ficusin);人类(Humans);微粒体, 肝(Microsomes, Liver);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1016/j.jpba.2017.04.026

PMID 28448889

发布时间 2018-12-02

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