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Synergistic activity of everolimus and 5-aza-2'-deoxycytidine in medullary thyroid carcinoma cell lines.

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第一作者： Giovanni,Vitale

第一单位： Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Italy.;Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS, Milan, Italy.

作者： Giovanni,Vitale ^[1] ; Alessandra,Dicitore ^[2] ; Daniele,Pepe ^[3] ; Davide,Gentilini ^[4] ; Elisa S,Grassi ^[5] ; Maria O,Borghi ^[6] ; Giulia,Gelmini ^[2] ; Maria C,Cantone ^[5] ; Germano,Gaudenzi ^[5] ; Gabriella,Misso ^[7] ; Anna M,Di Blasio ^[4] ; Leo J,Hofland ^[8] ; Michele,Caraglia ^[7] ; Luca,Persani ^[1]

作者单位： Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Italy.;Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS, Milan, Italy. ^[1] Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano IRCCS, Milan, Italy. ^[2] I-BioStat, Hasselt University, Belgium. ^[3] Molecular Biology Laboratory, Istituto Auxologico Italiano, Milan, Italy. ^[4] Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Italy. ^[5] Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Italy.;Experimental Laboratory of Immuno-rheumatologic Researches, Istituto Auxologico Italiano IRCCS, Milan, Italy. ^[6] Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, Italy. ^[7] Section Endocrinology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands. ^[8]

关键词 5-aza-2′-deoxycytidine NGFR everolimus mTOR medullary thyroid cancer neurotrophin pathway