Association of regulatory TPH2 polymorphisms with higher reduction in depressive symptoms in children and adolescents treated with fluoxetine.

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作者： Patricia,Gassó ^[1] ; Natalia,Rodríguez ^[2] ; Daniel,Boloc ^[2] ; Ana,Blázquez ^[3] ; Teresa,Torres ^[2] ; Ana,Gortat ^[2] ; Maria Teresa,Plana ^[3] ; Amalia,Lafuente ^[4] ; Sergi,Mas ^[4] ; Joan Albert,Arnaiz ^[5] ; Luisa,Lázaro ^[6]

作者单位： Department of Basic Clinical Practice, Unit of Pharmacology, University of Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. ^[1] Department of Basic Clinical Practice, Unit of Pharmacology, University of Barcelona, Spain. ^[2] Department of Child and Adolescent Psychiatry and Psychology, Institute of Neurosciences, Hospital Clinic de Barcelona, Spain. ^[3] Department of Basic Clinical Practice, Unit of Pharmacology, University of Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Spain. ^[4] Department of Basic Clinical Practice, Unit of Pharmacology, University of Barcelona, Spain; Clinical Pharmacology Department, Hospital Clinic de Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address: JAARNAIZ@clinic.ub.es. ^[5] Department of Child and Adolescent Psychiatry and Psychology, Institute of Neurosciences, Hospital Clinic de Barcelona, Spain; Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Spain. Electronic address: LLAZARO@clinic.cat. ^[6]

关键词 Children Fluoxetine Pharmacogenetics Polymorphism TPH2 rs34517220