Thermosensitive Gel-Based Formulation for Intratumoral Delivery of Toll-Like Receptor 7/8 Dual Agonist, MEDI9197.
第一作者:
Amir,Fakhari
第一单位:
Drug Delivery and Device Development, MedImmune LLC, Gaithersburg, Maryland 20878. Electronic address: fakharia@medimmune.com.
作者:
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞因子类(Cytokines);迟效制剂(Delayed-Action Preparations);药物释放系统(Drug Delivery Systems);女(雌)性(Female);凝胶类(Gels);杂环化合物, 3环(Heterocyclic Compounds, 3-Ring);黑色素瘤, 实验性(Melanoma, Experimental);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);泊洛沙姆(Poloxamer);硬脂酸类(Stearic Acids);温度(Temperature);Toll样受体7(Toll-Like Receptor 7);Toll样受体8(Toll-Like Receptor 8)
DOI
10.1016/j.xphs.2017.04.041
PMID
28456734
发布时间
2018-11-13
- 浏览33
Journal of pharmaceutical sciences
2037-2045页
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