The integrity of PRRSV nucleocapsid protein is necessary for up-regulation of optimal interleukin-10 through NF-κB and p38 MAPK pathways in porcine alveolar macrophages.

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第一作者： Jiang,Yu

第一单位： Shandong Academy of Agricultural Sciences, Jinan 250100, China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan 250022, China.

作者： Jiang,Yu ^[1] ; Yanyan,Liu ^[2] ; Yuyu,Zhang ^[1] ; Xiwang,Zhu ^[2] ; Sufang,Ren ^[1] ; Lihui,Guo ^[1] ; Xing,Liu ^[3] ; Wenbo,Sun ^[1] ; Zhi,Chen ^[1] ; Xiaoyan,Cong ^[1] ; Lei,Chen ^[1] ; Jianli,Shi ^[1] ; Yijun,Du ^[1] ; Jun,Li ^[1] ; Jiaqiang,Wu ^[4] ; Jinbao,Wang ^[5]

作者单位： Shandong Academy of Agricultural Sciences, Jinan 250100, China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan 250022, China. ^[1] Shandong Academy of Agricultural Sciences, Jinan 250100, China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan 250022, China; School of Life Sciences, Shandong University, Jinan 250100, China. ^[2] Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biologicals Engineering and Technology, Ministry of Agriculture, National Center for Engineering Research of Veterinary Bio-products, Nanjing 210014, China. ^[3] Shandong Academy of Agricultural Sciences, Jinan 250100, China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan 250022, China; School of Life Sciences, Shandong University, Jinan 250100, China. Electronic address: jqwu75@163.com. ^[4] Shandong Academy of Agricultural Sciences, Jinan 250100, China; Shandong Key Lab of Animal Disease Control and Breeding, Jinan 250022, China; School of Life Sciences, Shandong University, Jinan 250100, China. Electronic address: jinbaowang@aliyun.com. ^[5]

关键词 Immunosuppression Interleukin-10 Nucleocapsid PRRSV Porcine alveolar macrophages