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Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease.

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第一作者： Xuan,Li

第一单位： UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.

作者： Xuan,Li ^[1] ; Ma'en,Obeidat ^[1] ; Guohai,Zhou ^[1] ; Janice M,Leung ^[2] ; Donald,Tashkin ^[3] ; Robert,Wise ^[4] ; John,Connett ^[5] ; Philippe,Joubert ^[6] ; Yohan,Bossé ^[7] ; Maarten,van den Berge ^[8] ; Corry-Anke,Brandsma ^[9] ; David C,Nickle ^[10] ; Ke,Hao ^[11] ; Peter D,Paré ^[2] ; Don D,Sin ^[12]

作者单位： UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada. ^[1] UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada; Department of Medicine (Pulmonary Division), University of British Columbia, Vancouver, British Columbia, Canada. ^[2] David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. ^[3] Johns Hopkins University School of Medicine, Baltimore, MD, USA. ^[4] University of Minnesota School of Public Health, Minneapolis, MN, USA. ^[5] Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Canada. ^[6] Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Canada; Department of Molecular Medicine, Laval University, Québec, Canada. ^[7] University of Groningen, University Medical Center Groningen, Department of Pulmonary Diseases, Groningen, The Netherlands. ^[8] University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands. ^[9] Merck & Co Inc, Rahway, NJ, USA. ^[10] Department of Genetics and Genomics Sciences, Mount Sinai School of Medicine, New York, NY, USA. ^[11] UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada; Department of Medicine (Pulmonary Division), University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: don.sin@hli.ubc.ca. ^[12]

关键词 COPD FEV1 Gene expression Ipratropium Lung Sex