High rate of improvement in serum matrix metalloproteinase-3 levels at 4 weeks predicts remission at 52 weeks in RA patients treated with adalimumab.

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第一作者： Yosuke,Hattori

第一单位： a Department of Orthopaedic Surgery and Rheumatology , National Hospital Organization Nagoya Medical Center , Nagoya , Japan.

作者： Yosuke,Hattori ^[1] ; Toshihisa,Kojima ^[2] ; Atsushi,Kaneko ^[1] ; Daihei,Kida ^[1] ; Yuji,Hirano ^[3] ; Takayoshi,Fujibayashi ^[4] ; Yuichiro,Yabe ^[5] ; Takeshi,Oguchi ^[6] ; Yasuhide,Kanayama ^[7] ; Hiroyuki,Miyake ^[8] ; Takefumi,Kato ^[9] ; Hideki,Takagi ^[10] ; Masatoshi,Hayashi ^[11] ; Takayasu,Ito ^[12] ; Tomone,Shioura ^[13] ; Nobunori,Takahashi ^[2] ; Hisato,Ishikawa ^[14] ; Koji,Funahashi ^[15] ; Naoki,Ishiguro ^[2]

作者单位： a Department of Orthopaedic Surgery and Rheumatology , National Hospital Organization Nagoya Medical Center , Nagoya , Japan. ^[1] b Department of Orthopaedic Surgery , Nagoya University Graduate School of Medicine , Nagoya , Japan. ^[2] c Department of Rheumatology , Toyohashi Municipal Hospital , Toyohashi , Japan. ^[3] d Department of Orthopaedic Surgery , Konan Kosei Hospital , Konan , Japan. ^[4] e Department of Rheumatology , Japan Community Healthcare Organization Tokyo Shinjuku Medical Center , Tokyo , Japan. ^[5] f Department of Orthopaedic Surgery , Anjo Kosei Hospital , Anjo , Japan. ^[6] g Department of Orthopedic Surgery and Rheumatology , Toyota Kosei Hospital , Toyota , Japan. ^[7] h Department of Orthopaedic Surgery , Ichinomiya Municipal Hospital , Ichinomiya , Japan. ^[8] i Kato Clinic , Okazaki , Japan. ^[9] j Department of Orthopaedic Surgery , Nagoya Central Hospital , Nagoya , Japan. ^[10] k Department of Rheumatology , Nagano Red Cross Hospital , Nagano , Japan. ^[11] l Ito Seikeigeka , Nagoya , Japan. ^[12] m Shizuoka Kosei Hospital , Shizuoka , Japan. ^[13] n Department of Orthopaedic Surgery , Japanese Red Cross Nagoya Daiichi Hospital , Nagoya , Japan. ^[14] o Department of Orthopaedic Surgery , Kariya Toyota General Hospital , Kariya , Japan. ^[15]

关键词 MMP-3 Rheumatoid arthritis adalimumab matrix metalloproteinase-3 remission