Understanding key features of bacterial restriction-modification systems through quantitative modeling.

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第一作者： Andjela,Rodic

第一单位： Institute of Physiology and Biochemistry, Faculty of Biology, University of Belgrade, Studentski trg 16, 11000, Belgrade, Serbia.;Multidisciplinary PhD program in Biophysics, University of Belgrade, Belgrade, Serbia.

作者： Andjela,Rodic ^[1] ; Bojana,Blagojevic ^[2] ; Evgeny,Zdobnov ^[3] ; Magdalena,Djordjevic ^[2] ; Marko,Djordjevic ^[4]

作者单位： Institute of Physiology and Biochemistry, Faculty of Biology, University of Belgrade, Studentski trg 16, 11000, Belgrade, Serbia.;Multidisciplinary PhD program in Biophysics, University of Belgrade, Belgrade, Serbia. ^[1] Institute of Physics Belgrade, University of Belgrade, Belgrade, Serbia. ^[2] Department of Genetic Medicine and Development, University of Geneva and Swiss Institute of Bioinformatics, Geneva, Switzerland. ^[3] Institute of Physiology and Biochemistry, Faculty of Biology, University of Belgrade, Studentski trg 16, 11000, Belgrade, Serbia. dmarko@bio.bg.ac.rs. ^[4]

关键词 Bacterial immune systems Biophysical modeling Gene expression dynamics Restriction-modification Transcription regulation

主题词 DNA限制修饰酶类(DNA Restriction-Modification Enzymes);脱氧核糖核酸酶类, 位点特异性Ⅱ型(Deoxyribonucleases, Type II Site-Specific);大肠杆菌(Escherichia coli);模型, 生物学(Models, Biological);蛋白质多聚化(Protein Multimerization);蛋白质结构, 四级(Protein Structure, Quaternary)

DOI 10.1186/s12918-016-0377-x

PMID 28466789

发布时间 2020-12-09

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