换一批Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.
第一作者：
Ahmet,Zehir
第一单位：
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
作者：
Ahmet,Zehir [1]
;
Ryma,Benayed [1]
;
Ronak H,Shah [1]
;
Aijazuddin,Syed [1]
;
Sumit,Middha [1]
;
Hyunjae R,Kim [1]
;
Preethi,Srinivasan [1]
;
Jianjiong,Gao [2]
;
Debyani,Chakravarty [2]
;
Sean M,Devlin [3]
;
Matthew D,Hellmann [4]
;
David A,Barron [5]
;
Alison M,Schram [4]
;
Meera,Hameed [1]
;
Snjezana,Dogan [1]
;
Dara S,Ross [1]
;
Jaclyn F,Hechtman [1]
;
Deborah F,DeLair [1]
;
JinJuan,Yao [1]
;
Diana L,Mandelker [1]
;
Donavan T,Cheng [1]
;
Raghu,Chandramohan [1]
;
Abhinita S,Mohanty [1]
;
Ryan N,Ptashkin [1]
;
Gowtham,Jayakumaran [1]
;
Meera,Prasad [1]
;
Mustafa H,Syed [1]
;
Anoop Balakrishnan,Rema [1]
;
Zhen Y,Liu [1]
;
Khedoudja,Nafa [1]
;
Laetitia,Borsu [1]
;
Justyna,Sadowska [1]
;
Jacklyn,Casanova [1]
;
Ruben,Bacares [1]
;
Iwona J,Kiecka [1]
;
Anna,Razumova [1]
;
Julie B,Son [1]
;
Lisa,Stewart [1]
;
Tessara,Baldi [1]
;
Kerry A,Mullaney [1]
;
Hikmat,Al-Ahmadie [1]
;
Efsevia,Vakiani [1]
;
Adam A,Abeshouse [3]
;
Alexander V,Penson [6]
;
Philip,Jonsson [6]
;
Niedzica,Camacho [1]
;
Matthew T,Chang [6]
;
Helen H,Won [1]
;
Benjamin E,Gross [2]
;
Ritika,Kundra [2]
;
Zachary J,Heins [2]
;
Hsiao-Wei,Chen [2]
;
Sarah,Phillips [2]
;
Hongxin,Zhang [2]
;
Jiaojiao,Wang [2]
;
Angelica,Ochoa [2]
;
Jonathan,Wills [7]
;
Michael,Eubank [7]
;
Stacy B,Thomas [7]
;
Stuart M,Gardos [7]
;
Dalicia N,Reales [8]
;
Jesse,Galle [8]
;
Robert,Durany [8]
;
Roy,Cambria [8]
;
Wassim,Abida [4]
;
Andrea,Cercek [4]
;
Darren R,Feldman [4]
;
Mrinal M,Gounder [4]
;
A Ari,Hakimi [9]
;
James J,Harding [4]
;
Gopa,Iyer [4]
;
Yelena Y,Janjigian [4]
;
Emmet J,Jordan [4]
;
Ciara M,Kelly [4]
;
Maeve A,Lowery [4]
;
Luc G T,Morris [9]
;
Antonio M,Omuro [10]
;
Nitya,Raj [4]
;
Pedram,Razavi [4]
;
Alexander N,Shoushtari [4]
;
Neerav,Shukla [11]
;
Tara E,Soumerai [4]
;
Anna M,Varghese [4]
;
Rona,Yaeger [4]
;
Jonathan,Coleman [8]
;
Bernard,Bochner [8]
;
Gregory J,Riely [4]
;
Leonard B,Saltz [4]
;
Howard I,Scher [4]
;
Paul J,Sabbatini [4]
;
Mark E,Robson [4]
;
David S,Klimstra [1]
;
Barry S,Taylor [12]
;
Jose,Baselga [13]
;
Nikolaus,Schultz [12]
;
David M,Hyman [4]
;
Maria E,Arcila [1]
;
David B,Solit [14]
;
Marc,Ladanyi [15]
;
Michael F,Berger [16]
作者单位：
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[1]
Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[2]
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[3]
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[4]
Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[5]
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.;Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[6]
Information Systems, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[7]
Clinical Research Administration, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[8]
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[9]
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[10]
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[11]
Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.;Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.;Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[12]
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.;Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[13]
Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.;Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.;Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[14]
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.;Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[15]
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.;Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.;Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[16]
医学主题词
队列研究(Cohort Studies);DNA, 肿瘤(DNA, Neoplasm);数据挖掘(Data Mining);可行性研究(Feasibility Studies);女(雌)性(Female);基因组学(Genomics);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);男(雄)性(Male);突变(Mutation);肿瘤转移(Neoplasm Metastasis);肿瘤(Neoplasms);前瞻性研究(Prospective Studies);序列分析, DNA(Sequence Analysis, DNA)
DOI
10.1038/nm.4333
PMID
28481359
发布时间
2025-09-26
- 浏览14
Nature medicine
Nature medicine
703-713页
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