换一批
换一批Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212.
作者：
主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);药物评价, 临床前(Drug Evaluation, Preclinical);抗药性, 肿瘤(Drug Resistance, Neoplasm);成纤维细胞(Fibroblasts);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);咪唑类(Imidazoles);黑色素瘤(Melanoma);小鼠(Mice);丝裂原活化蛋白激酶1(Mitogen-Activated Protein Kinase 1);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);器官特异性(Organ Specificity);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);吡啶类(Pyridines);嘧啶类(Pyrimidines);信号传导(Signal Transduction);皮肤肿瘤(Skin Neoplasms);构效关系(Structure-Activity Relationship);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1080/15384101.2017.1325046
PMID
28489985
发布时间
2022-03-31
- 浏览94
Cell cycle (Georgetown, Tex.)
1790-1799页
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