Novel translational therapeutic strategy by sequencing primary liver cancer genomes.

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作者： Georgios K,Glantzounis ^[1] ; Ioannis D,Kyrochristos ^[1] ; Demosthenes E,Ziogas ^[2] ; Efstathios G,Lykoudis ^[2] ; Dimitrios H,Roukos ^[3]

作者单位： Department of Surgery, Ioannina University Hospital, Ioannina, Greece. ^[1] Centre for Biosystems & Genome Network Medicine, Ioannina University, Ioannina, Greece. ^[2] Department of Surgery, 'G. Hatzikosta' General Hospital, Ioannina, Greece. ^[3] Department of Plastic Surgery, Ioannina University Hospital, Ioannina, Greece. ^[4] Unit of Systems Biology, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece. ^[5]

关键词 cancer genome drugs hepatocellular cancer intrahepatic cholangiocarcinoma next-generation sequencing novel oncotargets umbrella and basket studies whole-exome sequencing whole-genome sequencing

主题词癌, 肝细胞(Carcinoma, Hepatocellular);抗药性, 肿瘤(Drug Resistance, Neoplasm);基因组, 人(Genome, Human);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);肝肿瘤(Liver Neoplasms);肿瘤蛋白质类(Neoplasm Proteins)

DOI 10.2217/fon-2017-0087

PMID 28492086

发布时间 2022-12-07

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