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PI3K/AKT/mTOR Signaling Mediates Valproic Acid-Induced Neuronal Differentiation of Neural Stem Cells through Epigenetic Modifications.

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第一作者： Xi,Zhang

第一单位： Key Laboratory of Neuroscience, Key Laboratory of Protein Modification and Degradation, Department of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China; Department of Neurology, Institute of Neuroscience, The Second Affiliated Hospital of Guangzhou Medical University, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou 510260, China.

作者： Xi,Zhang ^[1] ; Xiaosong,He ^[1] ; Qingqing,Li ^[1] ; Xuejian,Kong ^[1] ; Zhenri,Ou ^[1] ; Le,Zhang ^[1] ; Zhuo,Gong ^[1] ; Dahong,Long ^[1] ; Jianhua,Li ^[2] ; Meng,Zhang ^[3] ; Weidong,Ji ^[4] ; Wenjuan,Zhang ^[5] ; Liping,Xu ^[1] ; Aiguo,Xuan ^[6]

作者单位： Key Laboratory of Neuroscience, Key Laboratory of Protein Modification and Degradation, Department of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China; Department of Neurology, Institute of Neuroscience, The Second Affiliated Hospital of Guangzhou Medical University, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou 510260, China. ^[1] Department of Physiology, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China. ^[2] Department of Physiology, Augusta University, Augusta 30912, USA. ^[3] The First Affiliated Hospital, Center for Translational Medicine, Sun Yat-sen University, Guangzhou 510080, China. ^[4] Department of Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China. ^[5] Key Laboratory of Neuroscience, Key Laboratory of Protein Modification and Degradation, Department of Anatomy, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, China; Department of Neurology, Institute of Neuroscience, The Second Affiliated Hospital of Guangzhou Medical University, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou 510260, China. Electronic address: xag2005@sohu.com. ^[6]

关键词 differentiation epigenetics mammalian target of rapamycin neural stem cells valproic acid