Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells.-论文-万方医学网

作者： Stefan,Somplatzki ^[1] ; Martina,Mühlenhoff ^[2] ; Andrea,Kröger ^[3] ; Rita,Gerardy-Schahn ^[2] ; Thomas,Böldicke ^[4]

作者单位： Helmholtz Centre for Infection Research, Structural and Functional Protein Research, Inhoffenstraße 7, D-38124, Braunschweig, Germany. ^[1] Institute of Cellular Chemistry, Hannover Medical School, D-30625, Hannover, Germany. ^[2] Helmholtz Centre for Infection Research, Group Innate Immunity and Infection, Inhoffenstraße 7, D-38124, Braunschweig, Germany. ^[3] Helmholtz Centre for Infection Research, Structural and Functional Protein Research, Inhoffenstraße 7, D-38124, Braunschweig, Germany. thomas.boeldicke@helmholtz-hzi.de. ^[4]

主题词动物(Animals);抗体(Antibodies);碱基序列(Base Sequence);CHO细胞(CHO Cells);细胞系, 肿瘤(Cell Line, Tumor);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);内质网(Endoplasmic Reticulum);HEK293细胞(HEK293 Cells);人类(Humans);免疫沉淀法(Immunoprecipitation);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);显微镜检查, 荧光(Microscopy, Fluorescence);神经细胞黏附分子类(Neural Cell Adhesion Molecules);质粒(Plasmids);横纹肌肉瘤(Rhabdomyosarcoma);唾液酸类(Sialic Acids);唾液酸转移酶类(Sialyltransferases);移植, 异种(Transplantation, Heterologous)

DOI 10.1186/s12896-017-0360-7

PMID 28499450

发布时间 2018-11-13

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Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells.

BMC biotechnology

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Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells.

BMC biotechnology

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BMC biotechnology

相关期刊

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