The phosphodiesterase 4 inhibitor apremilast inhibits Th1 but promotes Th17 responses induced by 6-sulfo LacNAc (slan) dendritic cells.
第一作者:
Stephanie,Oehrl
第一单位:
Department of Dermatology, University Hospital Heidelberg, Germany.
作者:
医学主题词
氨基糖类(Amino Sugars);共同培养技术(Coculture Techniques);环AMP(Cyclic AMP);细胞因子类(Cytokines);树突细胞(Dendritic Cells);人类(Humans);免疫因子类(Immunologic Factors);白细胞, 单核(Leukocytes, Mononuclear);核受体亚家族1, F组, 成员3(Nuclear Receptor Subfamily 1, Group F, Member 3);磷酸二酯酶4抑制剂(Phosphodiesterase 4 Inhibitors);银屑病(Psoriasis);T盒域蛋白质类(T-Box Domain Proteins);Th1细胞(Th1 Cells);Th17细胞(Th17 Cells);沙立度胺(Thalidomide);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1016/j.jdermsci.2017.04.005
PMID
28499587
发布时间
2025-01-03
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