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首页> Archives of biochemistry and biophysics> Thiamine potentiates chemoprotective effects of ibuprofen in DEN induced hepatic cancer via alteration of oxidative stress and inflammatory mechanism.

Thiamine potentiates chemoprotective effects of ibuprofen in DEN induced hepatic cancer via alteration of oxidative stress and inflammatory mechanism.

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作者： Muhammad,Afzal ^[1] ; Imran,Kazmi ^[2] ; Ruqaiyah,Khan ^[3] ; Poonam,Rana ^[3] ; Vikas,Kumar ^[4] ; Fahad A,Al-Abbasi ^[5] ; Mazin A,Zamzami ^[5] ; Firoz,Anwar ^[6]

作者单位： Department of Pharmacology, College of Pharmacy, Al Jouf University, Sakaka, Kingdom of Saudi Arabia. ^[1] Glocal School of Pharmacy, Glocal University, Saharanpur, Uttar Pradesh, 247121, India. Electronic address: kazmiimran2005@gmail.com. ^[2] Siddhartha Institute of Pharmacy, Dehradun, India. ^[3] Natural Product Drug Discovery Laboratory, Department of Pharmaceutical Sciences, Faculty of Health Sciences, Sam Higginbottom Institute of Agriculture, Technology and Sciences, Allahabad, Uttar Pradesh, India. ^[4] Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. ^[5] Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. Electronic address: firoz_anwar2000@yahoo.com. ^[6]

关键词 Alfa-fetoprotein Diethyl nitrosamine Ibuprofen Interleukin-1β Serum biochemical parameters Thiamine

主题词动物(Animals);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);抗致癌药(Anticarcinogenic Agents);细胞因子类(Cytokines);二乙基亚硝胺(Diethylnitrosamine);药物协同作用(Drug Synergism);布洛芬(Ibuprofen);白细胞介素1β(Interleukin-1beta);肝(Liver);肝肿瘤(Liver Neoplasms);男(雄)性(Male);氧化性应激(Oxidative Stress);大鼠, Wistar(Rats, Wistar);硫胺素(Thiamine);复合维生素B(Vitamin B Complex)

DOI 10.1016/j.abb.2017.05.006

PMID 28501584

发布时间 2018-02-09

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Archives of biochemistry and biophysics

2017年623-624卷

58-63页

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