Stability behavior of antiretroviral drugs and their combinations. 7: Comparative degradation pathways of lamivudine and emtricitabine and explanation to their differential degradation behavior by density functional theory.

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作者： Moolchand,Kurmi ^[1] ; Saranjit,Singh ^[2]

作者单位： Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S., Nagar 160 062, Punjab, India. ^[1] Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S., Nagar 160 062, Punjab, India. Electronic address: ssingh@niper.ac.in. ^[2]

关键词 Density functional theory Emtricitabine Lamivudine Mass spectrometry Stress testing

主题词腺嘌呤(Adenine);抗HIV药(Anti-HIV Agents);脱氧胞苷(Deoxycytidine);双脱氧核苷类(Dideoxynucleosides);复方合剂(Drug Combinations);HIV感染(HIV Infections);拉米夫定(Lamivudine)

DOI 10.1016/j.jpba.2017.04.034

PMID 28511058

发布时间 2018-12-02

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