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Aptamer-mediated gene therapy enhanced antitumor activity against human hepatocellular carcinoma in vitro and in vivo.

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第一作者： Shuangli,Xiao

第一单位： Department of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China.

作者： Shuangli,Xiao ^[1] ; Zhongbing,Liu ^[1] ; Ruolan,Deng ^[1] ; Chunhong,Li ^[1] ; Shaozhi,Fu ^[2] ; Guilan,Chen ^[3] ; Xiaoqin,Zhang ^[1] ; Famin,Ke ^[1] ; Siyun,Ke ^[4] ; Xin,Yu ^[1] ; Shurong,Wang ^[1] ; Zhirong,Zhong ^[5]

作者单位： Department of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China. ^[1] Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China. ^[2] The Key Laboratory of Medical Electrophysiology of Ministry of Education, Southwest Medical University, Luzhou, Sichuan 646000, China. ^[3] Luzhou Senior High School, Luzhou, Sichuan 646000, China. ^[4] Department of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China. Electronic address: zhongzr@swmu.edu.cn. ^[5]

关键词 Antitumor activity Aptamer EpDT3 Gene delivery system Human hepatocellular carcinoma PTEN Recombinant adenovirus