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Resistance to malaria through structural variation of red blood cell invasion receptors.

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第一作者: Ellen M,Leffler
第一单位: Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.;Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
作者单位: Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.;Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK. [1] Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. [2] Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK. [3] Medical Research Council Unit, Atlantic Boulevard, Fajara, Post Office Box 273, The Gambia. [4] Medical Research Council Unit, Atlantic Boulevard, Fajara, Post Office Box 273, The Gambia.;Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. [5] Medical Research Council Unit, Atlantic Boulevard, Fajara, Post Office Box 273, The Gambia.;Royal Victoria Teaching Hospital, Independence Drive, Post Office Box 1515, Banjul, The Gambia. [6] Centre National de Recherche et de Formation sur le Paludisme (CNRFP), 01 BP 2208 Ouagadougou 01, Burkina Faso. [7] University of Rome La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy. [8] Department of Medical Laboratory Sciences, University of Buea, Post Office Box 63, Buea, South West Region, Cameroon. [9] Department of Biochemistry and Molecular Biology, University of Buea, Post Office Box 63, Buea, South West Region, Cameroon. [10] Kenyan Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Post Office Box 230-80108, Kilifi, Kenya.;Nuffield Department of Medicine, NDM Research Building, Roosevelt Drive, Headington, Oxford OX3 7FZ, UK. [11] Kenyan Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Post Office Box 230-80108, Kilifi, Kenya. [12] Kenyan Medical Research Institute (KEMRI)-Wellcome Trust Research Programme, Post Office Box 230-80108, Kilifi, Kenya.;Faculty of Medicine, Department of Medicine, Imperial College, Exhibition Road, London SW7 2AZ, UK. [13] Joint Malaria Programme, Kilimanjaro Christian Medical Centre, Post Office Box 2228, Moshi, Tanzania.;Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. [14] Joint Malaria Programme, Kilimanjaro Christian Medical Centre, Post Office Box 2228, Moshi, Tanzania.;Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.;National Institute for Medical Research, Mwanza Research Centre, Mwanza City, Tanzania. [15] Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. [16] Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Queen Elizabeth Central Hospital, College of Medicine, Post Office Box 30096, Chichiri, Blantyre 3, Malawi. [17] Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Queen Elizabeth Central Hospital, College of Medicine, Post Office Box 30096, Chichiri, Blantyre 3, Malawi.;Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK. [18] Blantyre Malaria Project, Queen Elizabeth Central Hospital, College of Medicine, Post Office Box 30096, Chichiri, Blantyre 3, Malawi.;College of Osteopathic Medicine, Michigan State University, East Lansing, MI 48824, USA. [19] International Blood Group Reference Laboratory, National Health Service (NHS) Blood and Transplant, 500 North Bristol Park, Filton, Bristol BS34 7QH, UK. [20] Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. chris.spencer@well.ox.ac.uk dominic.kwiatkowski@sanger.ac.uk. [21] Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK. chris.spencer@well.ox.ac.uk dominic.kwiatkowski@sanger.ac.uk.;Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK. [22]
DOI 10.1126/science.aam6393
PMID 28522690
发布时间 2025-05-30
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