Impaired mitophagy facilitates mitochondrial damage in Danon disease.

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作者： Sherin I,Hashem ^[1] ; Anne N,Murphy ^[2] ; Ajit S,Divakaruni ^[2] ; Matthew L,Klos ^[3] ; Bradley C,Nelson ^[1] ; Emily C,Gault ^[1] ; Teisha J,Rowland ^[4] ; Cynthia N,Perry ^[1] ; Yusu,Gu ^[1] ; Nancy D,Dalton ^[1] ; William H,Bradford ^[1] ; Eric J,Devaney ^[3] ; Kirk L,Peterson ^[1] ; Kenneth L,Jones ^[5] ; Matthew R G,Taylor ^[4] ; Ju,Chen ^[1] ; Neil C,Chi ^[6] ; Eric D,Adler ^[7]

作者单位： Department of Medicine, Division of Cardiology, University of California San Diego, La Jolla, CA, USA. ^[1] Department of Pharmacology, University of California San Diego, La Jolla, CA, USA. ^[2] Department of Surgery, University of California San Diego, La Jolla, CA, USA. ^[3] Cardiovascular Institute, Adult Medical Genetics Program, University of Colorado Denver, Aurora, CO, USA. ^[4] Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplant, University of Colorado Denver, Aurora, CO, USA. ^[5] Department of Medicine, Division of Cardiology, University of California San Diego, La Jolla, CA, USA; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA. ^[6] Department of Medicine, Division of Cardiology, University of California San Diego, La Jolla, CA, USA. Electronic address: eradler@ucsd.edu. ^[7]

关键词 Autophagy Cardiomyocyte Heart failure Mitochondria hiPSC