Two cycles of plasma rich in growth factors (PRGF-Endoret) intra-articular injections improve stiffness and activities of daily living but not pain compared to one cycle on patients with symptomatic knee osteoarthritis.

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第一作者： Víctor,Vaquerizo

第一单位： Department of Orthopaedic Surgery, Príncipe de Asturias University Hospital, Ctra. Alcalá-Meco s/n, 28805, Alcalá de Henares, Spain. vaquerizovictor@yahoo.es.

作者： Víctor,Vaquerizo ^[1] ; Sabino,Padilla ^[2] ; José Javier,Aguirre ^[3] ; Leire,Begoña ^[2] ; Gorka,Orive ^[4] ; Eduardo,Anitua ^[2]

作者单位： Department of Orthopaedic Surgery, Príncipe de Asturias University Hospital, Ctra. Alcalá-Meco s/n, 28805, Alcalá de Henares, Spain. vaquerizovictor@yahoo.es. ^[1] BTI Biotechnology Institute ImasD, S.L. C/Jacinto Quincoces, 39, 01007, Vitoria, Spain. ^[2] Pathology Department, Hospital Universitario de Álava (HUA), C/José Achotegui s/n, 01008, Vitoria, Spain. ^[3] BTI Biotechnology Institute ImasD, S.L. C/Jacinto Quincoces, 39, 01007, Vitoria, Spain. gorka.orive@ehu.es.;Laboratory of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of the Basque Country, Vitoria, Spain. gorka.orive@ehu.es.;Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN, SLFPB-EHU, Vitoria, Spain. gorka.orive@ehu.es. ^[4]

关键词 Growth factors Osteoarthritis PRGF Pain Regeneration