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Mining for osteogenic surface topographies: In silico design to in vivo osseo-integration.

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第一作者： Frits F B,Hulshof

第一单位： MIRA Institute for Biomedical Technology and Technical Medicine, Department of Biomaterials Science and Technology, University of Twente, Enschede, The Netherlands; MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Cell Biology -Inspired Tissue Engineering, Maastricht, The Netherlands.

作者： Frits F B,Hulshof ^[1] ; Bernke,Papenburg ^[2] ; Aliaksei,Vasilevich ^[3] ; Marc,Hulsman ^[4] ; Yiping,Zhao ^[2] ; Marloes,Levers ^[2] ; Natalie,Fekete ^[2] ; Meint,de Boer ^[5] ; Huipin,Yuan ^[6] ; Shantanu,Singh ^[7] ; Nick,Beijer ^[3] ; Mark-Anthony,Bray ^[7] ; David J,Logan ^[7] ; Marcel,Reinders ^[4] ; Anne E,Carpenter ^[7] ; Clemens,van Blitterswijk ^[8] ; Dimitrios,Stamatialis ^[9] ; Jan,de Boer ^[10]

作者单位： MIRA Institute for Biomedical Technology and Technical Medicine, Department of Biomaterials Science and Technology, University of Twente, Enschede, The Netherlands; MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Cell Biology -Inspired Tissue Engineering, Maastricht, The Netherlands. ^[1] Materiomics BV, Maastricht, The Netherlands. ^[2] MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Cell Biology -Inspired Tissue Engineering, Maastricht, The Netherlands. ^[3] Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands. ^[4] MESA+Institute for Nanotechnology, University of Twente, Enschede, The Netherlands. ^[5] Xpand Biotechnology BV, Bilthoven, The Netherlands. ^[6] Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA. ^[7] MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Complex Tissue Regeneration, University of Maastricht, Maastricht, The Netherlands. ^[8] MIRA Institute for Biomedical Technology and Technical Medicine, Department of Biomaterials Science and Technology, University of Twente, Enschede, The Netherlands. ^[9] MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Cell Biology -Inspired Tissue Engineering, Maastricht, The Netherlands. Electronic address: jan.deboer@maastrichtuniversity.nl. ^[10]

关键词 Bone implants Computational modeling Differentiation High-throughput screening Micro-fabrication Surface topography