Dasatinib rapidly induces deep molecular response in chronic-phase chronic myeloid leukemia patients who achieved major molecular response with detectable levels of BCR-ABL1 transcripts by imatinib therapy.

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第一作者： Masayuki,Shiseki

第一单位： Department of Hematology, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan. shisekim@dh.twmu.ac.jp.

作者： Masayuki,Shiseki ^[1] ; Chikashi,Yoshida ^[2] ; Naoki,Takezako ^[3] ; Akira,Ohwada ^[4] ; Takashi,Kumagai ^[5] ; Kaichi,Nishiwaki ^[6] ; Akira,Horikoshi ^[7] ; Tetsuya,Fukuda ^[8] ; Hina,Takano ^[9] ; Yasuji,Kouzai ^[10] ; Junji,Tanaka ^[11] ; Satoshi,Morita ^[12] ; Junichi,Sakamoto ^[13] ; Hisashi,Sakamaki ^[14] ; Koiti,Inokuchi ^[15]

作者单位： Department of Hematology, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan. shisekim@dh.twmu.ac.jp. ^[1] Department of Hematology, National Hospital Organization Mito Medical Center, Ibaraki, Japan. ^[2] Department of Hematology, National Disaster Medical Center, Tokyo, Japan. ^[3] Department of Hematology, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan. ^[4] Department of Hematology, Ohme Municipal General Hospital, Tokyo, Japan. ^[5] Clinical Oncology and Hematology, Jikei University Kashiwa Hospital, Chiba, Japan. ^[6] Department of General Internal Medicine, Nerima-Hikarigaoka Hospital, Tokyo, Japan. ^[7] Department of Hematology, Tokyo Medical and Dental University, Tokyo, Japan. ^[8] Department of Hematology, Japanese Red Cross Musashino Hospital, Tokyo, Japan. ^[9] Hematology Department, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan. ^[10] Department of Hematology, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan. ^[11] Department of Biomedical Statistics and Bioinformatics, Kyoto University Graduate School of Medicine, Kyoto, Japan. ^[12] Tokai Central Hospital, Gifu, Japan. ^[13] Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan. ^[14] Division of Hematology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan. ^[15]

关键词 Chronic myeloid leukemia Dasatinib Deep molecular response