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Multidrug ABC transporter Cdr1 of Candida albicans harbors specific and overlapping binding sites for human steroid hormones transport.

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第一作者： Pratima,Baghel

第一单位： Departments of Biosciences and Bioengineering, Integral University, Lucknow, U.P. 226026, India; Amity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon 122413, Haryana, India.

作者： Pratima,Baghel ^[1] ; Manpreet Kaur,Rawal ^[2] ; Mohammad Firoz,Khan ^[3] ; Sobhan,Sen ^[3] ; Mohammed Haris,Siddiqui ^[4] ; Vincent,Chaptal ^[5] ; Pierre,Falson ^[6] ; Rajendra,Prasad ^[7]

作者单位： Departments of Biosciences and Bioengineering, Integral University, Lucknow, U.P. 226026, India; Amity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon 122413, Haryana, India. ^[1] Gargi College, University of Delhi, New Delhi 110049, India. ^[2] School of Physical Sciences, Jawaharlal Nehru University, New Delhi 110067, India. ^[3] Departments of Biosciences and Bioengineering, Integral University, Lucknow, U.P. 226026, India. ^[4] Drug Resistance & Membrane Proteins Team, Molecular Microbiology and Structural Biochemistry Laboratory, CNRS-Lyon 1 University Research Unit No. 5086, Institut de Biologie et Chimie des Protéines, Lyon, France. ^[5] Drug Resistance & Membrane Proteins Team, Molecular Microbiology and Structural Biochemistry Laboratory, CNRS-Lyon 1 University Research Unit No. 5086, Institut de Biologie et Chimie des Protéines, Lyon, France. Electronic address: pierre.falson@ibcp.fr. ^[6] Amity Institute of Integrative Sciences and Health, Amity University Haryana, Gurgaon 122413, Haryana, India. Electronic address: rprasad@ggn.amity.edu. ^[7]

关键词 ABC transporter Candida albicans Cdr1p Corticosterone Molecular docking β-estradiol

医学主题词 ATP结合匣式转运子(ATP-Binding Cassette Transporters);结合部位(Binding Sites);生物转运(Biological Transport);白色念珠菌(Candida albicans);真菌蛋白质类(Fungal Proteins);激素类(Hormones);人类(Humans);脂类(Lipids);膜转运蛋白质类(Membrane Transport Proteins);蛋白质结构, 二级(Protein Structure, Secondary);甾类(Steroids)

DOI 10.1016/j.bbamem.2017.05.011

PMID 28559186

发布时间 2018-09-17

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Biochimica et biophysica acta. Biomembranes

2017年1859卷10期

1778-1789页

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Biochimica et biophysica acta. Biomembranes

2017年1859卷10期

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Multidrug ABC transporter Cdr1 of Candida albicans harbors specific and overlapping binding sites for human steroid hormones transport.

Biochimica et biophysica acta. Biomembranes

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Multidrug ABC transporter Cdr1 of Candida albicans harbors specific and overlapping binding sites for human steroid hormones transport.

Biochimica et biophysica acta. Biomembranes

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Biochimica et biophysica acta. Biomembranes

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