Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.

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第一作者： Claudio,Isella

第一单位： Department of Oncology, University of Torino School of Medicine, 10060 Candiolo Torino, Italy.

作者： Claudio,Isella ^[1] ; Francesco,Brundu ^[2] ; Sara E,Bellomo ^[3] ; Francesco,Galimi ^[1] ; Eugenia,Zanella ^[2] ; Roberta,Porporato ^[1] ; Consalvo,Petti ^[2] ; Alessandro,Fiori ^[2] ; Francesca,Orzan ^[2] ; Rebecca,Senetta ^[1] ; Carla,Boccaccio ^[2] ; Elisa,Ficarra ^[2] ; Luigi,Marchionni ^[1] ; Livio,Trusolino ^[2] ; Enzo,Medico ^[2] ; Andrea,Bertotti ^[4]

作者单位： Department of Oncology, University of Torino School of Medicine, 10060 Candiolo Torino, Italy. ^[1] Candiolo Cancer Institute-FPO IRCCS, 10060 Candiolo Torino, Italy. ^[2] Department of Control and Computer Engineering, Torino School of Engineering, 10129 Torino, Italy. ^[3] Department of Medical Sciences, University of Torino School of Medicine, 10060 Candiolo Torino, Italy. ^[4] Department of Oncology, Johns Hopkins University, Baltimore, 21287 Maryland, USA. ^[5] National Institute of Biostructures and Biosystems, INBB, 00136 Rome, Italy. ^[6]

主题词动物(Animals);细胞谱系(Cell Lineage);结直肠肿瘤(Colorectal Neoplasms);上皮-间质转化(Epithelial-Mesenchymal Transition);女(雌)性(Female);基因表达谱(Gene Expression Profiling);基因, p53(Genes, p53);糖酵解(Glycolysis);人类(Humans);胰岛素样生长因子Ⅱ(Insulin-Like Growth Factor II);男(雄)性(Male);小鼠(Mice);微卫星不稳定性(Microsatellite Instability);突变(Mutation);预后(Prognosis);信号传导(Signal Transduction);间质细胞(Stromal Cells);转化生长因子β(Transforming Growth Factor beta)

DOI 10.1038/ncomms15107

PMID 28561063

发布时间 2022-03-18

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Nature communications

2017年8卷

15107页

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Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.

Nature communications

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Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.

Nature communications

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Nature communications

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