A Phase 2 randomized, observer-blind, placebo-controlled, dose-ranging trial of aluminum-adjuvanted respiratory syncytial virus F particle vaccine formulations in healthy women of childbearing age.

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作者： Allison,August ^[1] ; Gregory M,Glenn ^[2] ; Eloi,Kpamegan ^[3] ; Somia P,Hickman ^[4] ; Dewal,Jani ^[5] ; Hanxin,Lu ^[6] ; D Nigel,Thomas ^[7] ; Judy,Wen ^[8] ; Pedro A,Piedra ^[9] ; Louis F,Fries ^[10]

作者单位： Novavax, Inc., 20 Firstfield Road, Gaithersburg, MD 20878, USA. Electronic address: allison.august11@gmail.com. ^[1] Novavax, Inc., 20 Firstfield Road, Gaithersburg, MD 20878, USA. Electronic address: gglenn@novavax.com. ^[2] Novavax, Inc., 20 Firstfield Road, Gaithersburg, MD 20878, USA. Electronic address: kepg47@gmail.com. ^[3] Novavax, Inc., 20 Firstfield Road, Gaithersburg, MD 20878, USA. Electronic address: shickman@novavax.com. ^[4] Novavax, Inc., 20 Firstfield Road, Gaithersburg, MD 20878, USA. Electronic address: djani@novavax.com. ^[5] Novavax, Inc., 20 Firstfield Road, Gaithersburg, MD 20878, USA. Electronic address: hlu@novavax.com. ^[6] Novavax, Inc., 20 Firstfield Road, Gaithersburg, MD 20878, USA. Electronic address: nthomas@novavax.com. ^[7] Novavax, Inc., 20 Firstfield Road, Gaithersburg, MD 20878, USA. Electronic address: jwen@novavax.com. ^[8] Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address: ppiedra@bcm.edu. ^[9] Novavax, Inc., 20 Firstfield Road, Gaithersburg, MD 20878, USA. Electronic address: lfries@novavax.com. ^[10]

关键词 Maternal immunization, transplacental antibody transfer Neutralizing antibody Palivizumab-competitive antibody RSV vaccine anti-F immunoglobulin G (IgG)