Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus.

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作者： Carlos A,Campos ^[1] ; Anna J,Bowen ^[1] ; Sung,Han ^[1] ; Brent E,Wisse ^[2] ; Richard D,Palmiter ^[1] ; Michael W,Schwartz ^[2]

作者单位： Department of Biochemistry, Howard Hughes Medical Institute, University of Washington, Seattle, Washington, USA. ^[1] Department of Medicine, University of Washington, Seattle, Washington, USA. ^[2]

主题词腺瘤状结肠息肉蛋白质(Adenomatous Polyposis Coli Protein);动物(Animals);厌食(Anorexia);行为, 动物(Behavior, Animal);体重(Body Weight);恶病质(Cachexia);降钙素基因相关肽(Calcitonin Gene-Related Peptide);癌, Lewis肺(Carcinoma, Lewis Lung);氯氮平(Clozapine);能量代谢(Energy Metabolism);女(雌)性(Female);疾病行为(Illness Behavior);男(雄)性(Male);金属内肽酶类(Metalloendopeptidases);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);肿瘤(Neoplasms);破伤风毒素(Tetanus Toxin);肿瘤细胞, 培养的(Tumor Cells, Cultured)

DOI 10.1038/nn.4574

PMID 28581479

发布时间 2018-12-02

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Nature neuroscience

2017年20卷7期

934-942页

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Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus.

Nature neuroscience

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Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus.

Nature neuroscience

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Nature neuroscience

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